Hair Restoration Blog

Often times we at US Hair Restoration receive calls and emails from individuals who are ashamed that they need a hair restoration for their balding situation and want to hide the fact they contacted us for advice. Although we are very sensitive to the needs of each individual who seeks our help, we also want to speak encouragement over their situation as well as give them new hope, confidence, and a fresh perception of what they are getting themselves into.

Modern technology has allowed us capabilities we did not have 50 years ago. Just as with vision problems, many have the disadvantage of wearing glasses. Although there are contact lenses as well, there is still a dependence upon outside tools for sight, which can be inconvenient. After many years, LASIK was developed which has solved this stubborn problem of fading eyesight which many, to this day continue to suffer from.

If someone chooses to undergo a LASIK procedure, does it make them an insecure person? Not in the least! Rather, they are using their resources to look their best and be as functionally independent as possible.

We always use the latest technology in hair restoration at US Hair Restoration, which was not available as recent as 10 years ago. The question to ask is, why not use it? Thousands are doing it every year with excellent results, and nobody is concerned if their hair is native or transplanted.  Hair loss is a disease, yes a common one and like any other diseases there are treatments for it.  The proper conclusion is that these individuals are no longer bald and don’t have the competitive disadvantage like those who decided to do nothing for their baldness.

 In the end we all must be ourselves and do whatever makes us feel our best. No matter what we do with our lives, there will always be someone who will be critical of whatever we do.  Regardless of what others may say, do whatever makes you feel good about yourself.  There are options available to you today that was not available to your ancestors.

Q:

I went to a couple different hair transplant doctors for evaluations when I was 24/25 and was told I have a juvenile hairline and that i have a good donor area and scalp laxity. The doctors recommended around 2000 grafts to fill in the diffused area at the time.

One of the doctors I visited told me to give propecia another try which I did for an additional six more months, but stopped because it seemed to have no effect and from my understanding it doesn’t really help with hair in the frontal area which was my main problem. I also did not want to risk getting any more health side effects from taking propecia.

During this time I was also taking biotin supplements which I had read are good for hair but they didn’t have any noticeable effects. I decided against getting a hair transplant because of my age and I wanted to see if the hair might grow back naturally (some people who have lost hair from accutane reported regrowing their hair several years after taking the medication).

I have a history of MPB in my family but it seems to be hit or miss. My grandfathers both had full heads of hair, my dad and 1 of his brothers are completely bald but another brother has a full head of hair. My mom has 1 brother who is bald and another with very thick hair and a low hairline (which my hair most closely resembled before taking accutane). I also have a brother who is 21 and has extremely thick hair like I used to with no signs of hair loss whatsoever.

A:

Male patterned baldness (MPB) is a progressive condition and it generally won’t get better without treatment.  The medications that are being used for the treatment of hair loss are generally for maintaining your existing hair and have preventative effects rather than restoring your hair at its full thickness like what you had in previous years.

A good hair transplant surgeon can help you realize what the best options for hair restoration are; whether it is a surgery or medication.  Using Accutane could cause hair loss as one side effect, but that is reversible within a few months after stopping it.  That is the most common case for medication related hair losses.

It is important for you to develop a good relationship with a qualified hair transplant surgeon whom you can trust.  Then let him walk you through this process.  Using medications for a while is a good idea and some patients respond well to using them.  Unfortunately the results are not permanent and most hair loss sufferers continue losing hair, but at a slower rate.  

You can use medications such as Propecia or Rogaine to minimize the speed of hair loss. When it is the time for a hair transplant you can consider that as another option as well.

Q:

My doctor put me on propecia at 21 when I told him about the hair loss and I took it for about six months but it had no effect on my hair loss. I also started to use rogaine around age 23/24 for a couple of months but stopped because it made my hair loss worse (before rogaine the majority of my hair loss was in the front area of my head and after using rogaine I started to lose hair on my crown as well). My hair loss has been pretty stable over the past 2-3 years and I have continued to lose some hair but nowhere near the amount I lost initially.

I wash my hair every 2-3 days and only notice about 20-30 hairs lost compared to the hundreds I lost early on. My hairline has not really been effected at all and my hair loss doesn’t seem to match any on the norwood scale, it is just diffused loss throughout and matches the description of many accutane users who have lost hair. I have also been using the ProThik concealer spray for the past 3 years which works great because my hair loss is diffuse and makes it unnoticeable, but the process of applying it in and combing through it causes my hair to get tangled and pulled out so I think over time that has also contributed to my hair loss. I lose far more hair putting in the concealer than I do washing it and combing through it naturally.

For the first 2 years of using it I would wash my hair and re-apply it daily, although over the past 6-8 months I have gone 2-3 days between washing and reapplying it and only lose 10-20 hairs when I comb through it in the morning. I am not sure how much of my hair loss in recent years has been caused by this but I suspect that is has had some effect, especially during the time I was applying the concealer every day.

A:

Many young hair loss patients may start taking finasteride or minoxidil when they see the signs of active hair loss in their early 20s.  That is the time most people lose hair at its maximum speed.  Medications such as finasteride or minoxidil are only to prevent hair loss or even in some cases slow down the process.  They are not to bring your hair back to where it was before you started the process of hair loss.

I recommend you visit a hair specialist who can perform microscopic evaluation of your scalp (miniaturization study).  That can give you more information about the type of your hair loss and the treatment methods. Having regular follow up visit with your hair doctor helps you to know whether or not your hair loss medication works.  You may also need a hair transplant when the time come and the time and type of the restoration surgery could be discussed with your hair transplant surgeon.

Q:

Hi Dr Mohebi,

Can you tell me your opinion on products like iGrow (low level laser therapy).

Thanks so much,

A:

Hello,

Unfortunately, there has been very little research done on different types of laser treatments for hair restoration and most studies are done in small numbers, lacking significant results.  As you already know there are a variety of devices such as laser combs, hoods, or brushes, yet most of these do not show significant improvement like I continue hearing from my patients who used them before. In spite of all this, I have heard a growing number of hair specialists talk about how they are seeing good results from the Laser Cap.

It seems like the best candidates are people with generalized hair thinning, as in typical female patterned hair loss.  Laser cap treats entire scalp with 224 individual red 5mw – 650 laser diodes.  This is much more coverage than the comb or other hand held laser devices offers.

I reviewed your file and based on your microscopic evaluation from 3 years ago you might be a good candidate.  However, I would like to evaluate your current condition with another microscopic evaluation.

Dr. Mohebi,

You classified my hair loss as class III.  I agree with the evaluation but given my family background I will be approaching more towards class V or VI.  My miniaturization % is 30 in both Top and Crown areas which means there is a sign of active hair loss.  Do you think we can arrange something to cover up those two areas as well?  Or, is my miniaturization level too low to have any type of procedure in those areas?

A:

You are class III of hair loss and as you said, you might be going toward class V or VI.  However, prescribed finasteride  you might change what is considered your genetic pattern by taking it.  I don’t recommend that we transplant hair in certain areas just in case you get lucky with the hair loss medications, you may never lose that existing hair.  If you progress to lose more hair, you can always have another hair transplant surgery in the future for those existing areas.  Even if you don’t continue hair loss medications, it is hard to predict if you will totally lose hair on the top and crown areas.  Your particular numbers for miniaturization is slightly more than normal.  A good decision today is a good decision tomorrow.

Dihydrotestosterone (DHT) is a byproduct of the hormone testosterone, which is formed in different areas such as the prostate gland and hair follicles.  Hair follicles which are susceptible to genetic male patterned baldness contain DHT receptors.  Over time as males produce more and more DHT the molecules affect hair follicles and cause them to become decrease in size, and eventually fall out permanently.

DHT and having the gene of male pattern baldness are the primary contributing factors for male pattern baldness. Women with female-pattern baldness, unlike men with male-pattern baldness, are usually not characterized by increased production rates of DHT due to their low levels of testosterone.  However if for any reason a woman has increased testosterone, she may develop female patterned baldness just like a man does with the same mechanism.

Hair in the areas that are prone to male patterned baldness such as corners, top and crown areas are loaded with DHT receptors in men with Androgenetic Alopecia.  However, the hair on donor areas such as back and sides do not have as much DHT receptors.  This is why hair is more permanent on the sides and back as opposed to the top and front.

The distinction in hair quality on different areas (donor vs. recipient) allows a hair transplant surgeon to remove hair from one area and transplant it to the balding portions of the scalp.  These transplanted hairs are permanent and won’t be affected by circulating DHT. Finasteride (Propecia) is a drug that blocks the conversion of testosterone to DHT by blocking the enzyme alpha reductase.  DHT levels in hair loss patients decrease when they are on Propecia and this helps maintain healthy hair, and this helps some of the miniaturized hair become stronger.

We recommend medical treatment with DHT blockers in many of our patients who undergo a hair transplant procedure to help maintaining their own hair in addition to restoring the balding areas with hair restoration surgery.

Avodart (dutasteride) and Propecia (finasteride) have recently been in the news for the report of some studies regarding their role in increased or decreased risk of prostate cancer.  Avodart and Propecia are both 5-alpha reductase inhibitors (5-ARI), which help prevent production of DHT (dihydrotestosterone).  This class of medications is indicated for the treatment of benign prostate (BPH) hypertrophy.  These DHT blockers also help with the prevention of male patterned hair loss and have been recommended and prescribed for hair loss treatment, for many years.

On one hand, several studies have indicated that DHT blockers could decrease the rate of prostate cancer.  On the other hand,  there are some studies that indicate they may increase the incidence of high-grade prostate cancers.  Those studies performed on both finasteride (7 years study) and dutasteride (4 years study).  It has been concluded that the patients who take DHT blockers should have prior knowledge of whether they have a lower risk of prostate cancer.  However, if the patient gets prostate cancer it might be in a category which is more advanced.

Doctors should be aware DHT blockers can decrease the levels of PSA artificially, so a small increase in PSA levels might reflect a higher activity of prostate tissue in comparison to patients who are not on DHT blockers. Overall, it is good practice to make sure all patients age 50 and older have a baseline PSA reading before they get started on finasteride.  This will determine their PSA levels before they begin taking medications, and the doctor will be able to monitor changes in PSA with greater precision.

Minoxidil (Rogaine) is one of the two proven treatments for hair loss along with hair transplant. Although minoxidil mechanism of action for hair growth is not fully understood, there have been several suggested mechanisms such as:

• Nitric oxide chemical agonist effect impactig scalp blood vessels
• Potassium channel opener causing hyperpolarization of follicles cell membrane
• Vasodilation possibly due to its nitric oxide effect

This new study is done in Department of Immunology of Kyungpook National University in Korea. The result of the study was published in The Journal of Dermatological Science shows a new mechanism for minoxidil as activator of β-catenin pathway in human dermal papilla cells, one of the two stem cells involved in development and growth of hair. The investigators announced that this mechanism could be an explanation for anagen prolongation effect of minoxidil.

The length of the actively growing hair in anagen phase (growth phase) is responsible for hair length. The investigators indicated that maintenance of β-catenin activity in the dermal papilla cells (DPCs) enables hair follicles to keep growing actively. Minoxidil or Rogain promotes hair growth in male patterned baldness suggesting that minoxidil can prolong the growth phase in hair life cycle.

The study is done in mouse model with application of 3% minoxidil for ten days. DPCs were transfected with β-catenin responsive TCF reporter plasmid. They showed that extension of anagen phase was significantly promoted after minoxidil application. The researchers concluded that minoxidil extends the anagen phase by activating β-catenin activity in the DPCs and that can be one of the main pathways in its hair growth or hair loss prevention mechanism.

Studies like this increase our understanding of hair loss and hair growth and over time can help hair restoration field to have more options to fight hair loss in a more efficient way.

Q:

Dear Dr. Mohebi,

I have recently learned that Finasteride injected into scalp and or taken orally not only stops hair loss but makes hair growth as well.  What is your opinion on the use of this  medication for female with hereditary pattern hair loss?  Is it safe, is it effective, do you use this method of treatment in your office?

 Thx.

A:

Finasteride injection is not approved nor recommended for male or female patterned hair loss and we do not recommend it.  Finasteride is prescribed for male patterned baldness in men and also it could be beneficial for women with hair loss secondary to hyperandrogenism (increased levels of male hormones) in women* to prevent or minimize the process of hair loss.  Finasteride (Propecia) is prescribed for typical forms of female patterned baldness without elevation of testosterone levels by some doctors.  However, there is no evidence to support its effectiveness on women with hair loss without elevated testosterone.

* The use of finasteride for women should be under a physician supervision and it is contraindicated in pregnant women.

Q:

Dear Dr. Mohebi,

I’m in my sixties and  consulted with you a year ago at your clinic, and had tests done, all normal.   I have had hair loss ever since I was nineteen years old.  The onset  was when I traveled to Europe, and it never stopped until in two cases:

1. With each pregnancy my hair loss almost completely stopped and gained a lot of hair back, but fell out after a few months during the period I was nursing my babies.

2.  About twenty years ago, I saw Dr. XX XX in Beverly Hills who prescribed Rogaine a solution that at the time wasn’t available over the counter.  After six weeks of application, I saw results, and after about four months I gained abundance of hair back, but started itching of scalps, and discontinued it.  When after being out of town for a while, I started seeking help, he had moved away, and couldn’t find that doctor.

For the past ten years or so that Rogaine has been readily available, I attempted using it even at the strength of male 5%, but have had no results.

Hair loss has been in my family, from my grandfather, on mother’s side, to my mother, and to me and now to my children.

My main questions are:

1. What was in the initial solution of Rogan that worked, and then over the counter ones didn’t work?
2. What is the latest preventive measures/solutions/hopes for this type of hair loss at least for my children’s generation?

Thank you kindly for your response,

A:

Hair loss medications such as Rogaine work only if you have active hair loss.  The effect is mostly preventative, but since it may make some of the miniaturized hair (finer hair that is in process of balding) thicker, patients may experience some enhancement in their hair bulk only for the first year of its use.

Some women with genetic female patterned hair loss may be good candidates for hair transplant surgery as long as they have protected (Permanent) hair on their donor area on the back and sides of the scalp.  Hair transplant in this group of patients should be done only if they are trying to reinforce a limited area of scalp.  However, a hair transplant is not a good idea if their goal is to increase hair density throughout a large area or entire scalp.

To be able to say what options are out there for your children, they need to be individually evaluated by a good dermatologist or a hair transplant surgeon and treatment options should be tailored to their individual needs.